19.07.12 18:00 Alter: 5 yrs

New manuscript accepted

Von: TN

How can measurement, monitoring, modelling and control advance cell culture in industrial biotechnology?

Carrondo M, Alves P, Carinhas N, Glassey J, Hesse F, Merten OW, Micheletti M, Noll T, Freitas Oliveira RM, Reichl U, Staby A, Teixeira A, Weichert H, Mandenius CF

Biotechnology Journal, accepted

Abstract:

This report highlights the potential of measurement, monitoring, modeling and control (M3C) methodologies in animal and human cell culture technology. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in M3C are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of
recommendations for targeting M3C research towards the industrial interests.